我們每日勞碌奔忙，有許多需要我們思考、記憶的事情。 遺憾的是，隨著年紀增長，我們的記憶力會逐漸退化。 即使是最簡單的信息，例如幾年前我們還能記得的名字、事件或任務，現在似乎忘得一乾二淨。 Prime™ 強化記憶配方旨在協助維持腦部正常的血液循環。 維持腦部正常血流，對於維持腦部正常功能是非常重要的。讓腦部進入最佳健康狀態可提升記憶力和思維活動能力。Prime™ 強化記憶配方有助集中注意力，讓頭腦不再混亂模糊。* 

本配方採用精選成分組合以提升記憶力並使腦部免受氧化壓力。硫辛酸具有抗氧化功能，可以清除腦部的自由基並阻止自由基引發的不良連鎖反應。 硫辛酸既具水溶性又具脂溶性，能夠重新生成內源性抗氧化劑，如維生素E、維生素C和穀胱甘肽，且能夠抑制氧化壓力。銀杏葉與乙醯左旋肉鹼有助維持腦部健康的血液循環。本配方經特別配製，可促進腦部血流以使頭腦維持最佳表現，並可為腦部補充抗氧化劑以抑制自由基的活動。*

Frequently Asked Questions About Cognitin™ Memory Support Formula :

If I am taking OPC-3 ®, can I take Cognitin ™ ?

The combination of the ingredient vinpocetine and OPC-3 may cause blood thinning, so if you are currently taking warfarin (Coumadin), other antiplatelet/anticoagulant, antidiabetic, chemotherapy or any other prescription drugs, or have an ongoing medical condition, you should consult their physician before taking this product.

I get sick taking pills on an empty stomach. Can I take this with food?

Cognitin should be taken with food to improve absorption of the active ingredients.

If I am already taking Vitamind, can I also take Cognitin?

The combination of Vitamind and Cognitin is not necessary or recommended. The vinpocetine in Cognitin may interact with the Ginkgo Biloba in Vitamind and may cause the blood to thin.

What other products complement Cognitin?

Isotonix ® Maximum ORAC, Isotonix Multivitamin, Heart Health Advanced CoQ10, and Isotonix Advanced B-Complex all complement Cognitin to produce optimal memory levels.

What are signs that I need Cognitin?

If you are elderly or if you routinely have difficulty when trying to recall a simple task, name, or event.

What portion of the brain does Cognitin affect*?

The entire brain.

What mechanisms does this formulation work by*?

· Aids in improving and enhancing memory

· Supports normal mental activity

· Inhibits oxidative stress on the brain

· Helps maintain healthy blood circulation within the brain (cerebral blood flow)

· Helps maintain normal brain physiology

· Supports overall cognitive performance

· Promotes healthy levels of acetylcholine (an important neurotransmitter in the brain)

· Helps minimize the effects of aging on the brain

When should I start to see a difference?

Possibly within two weeks.

Key Ingredients Found In Cognitin™ Memory Support Formula :

Acetyl L-Carnitine: 500 mg

Acetyl L-Carnitine (ALC) is able to travel through the blood-brain barrier where it supports the normal formation of the brain chemical acetylcholine; it promotes the efficient operation of cells by helping them stay clear of toxic fatty-acid metabolites; and it helps maintain normal brain physiology.*

Chemical messengers like neurotransmitters are vital to maintaining cognitive function yet often decline with age. Studies have shown that ALC promotes overall cognitive performance. ALC promotes normal cognitive function by helping to maintain brain energy production, phospholipid metabolism and acetyl coenzyme A levels. Acetyl coenzyme A is used by the body to re-synthesize acetylcholine.*

Alpha-lipoic acid: 100 mg

Deep within the tissue, alpha-lipoic acid is a coenzyme that, together with pyrophosphatase, promotes normal carbohydrate metabolism and production of adenosine triphosphate (ATP). Deep within the tissues of the brain, alpha-lipoic acid and the metabolite, dihydrolipoic acid (DHLA), have antioxidant components, which help to neutralize damaging free radicals.*

Alpha-lipoic acid is both water and fat-soluble and can regenerate endogenous antioxidants, such as vitamin E, vitamin C, and glutathione, and prevent oxidative stress. Alpha-lipoic acid is about 30 percent absorbed from dietary or supplemental sources, and is reduced to DHLA in many tissues.*

Vinpocetine (Viagra for the Brain): 20 mg

Vinpocetine appears to have antioxidant components and supports normal blood flow, which may be beneficial to healthy brain function. Preliminary evidence indicates that vinpocetine supports cerebral circulation and promotes glucose and oxygen consumption by the brain. Vinpocetine's age management benefits may include improved concentration.*

Scientific Studies Which Support Cognitin™ Memory Support Formula :

Acetyl-L-Carnitine and Alpha-Lipoic Acid: A Possible Anti-aging Combination Aug 2002, Vol. 8, No. 4: 242-245 Balestreri, R., et al. A double-blind placebo controlled evaluation of the safety and efficacy of vinpocetine in the treatment of patients with chronic vascular senile cerebral dysfunction. J Am Geriatric Society. 35(5):425-430, 1987. Bhatti, J., et al. Vinpocetinee effects on cognitive impairments produced by flunitrazepam. Int Clin Psychopharmacol. 2:325-331, 1987. Bigini, P., et al. Acetyl-L-carnitine shows neuroprotective and neurotrophic activity in primary culture of rat embryo motoneurons. Neurosci Lett. 329:334, 2002 Calvani, M., et al. Action of acetyl-L-carnitine in neurodegeneration and Alzheimer’s disease. Annals of the New York Academy of Sciences (USA). 663:483-486, 1993. Coleston, D. M., et al. Possible memory-enhancing properties of vinpocetine. Drug Dev Res. 14:191-193, 1988. De Simone, R., et al. Effect of acetyl-L-carnitine on forebrain cholinergic neurons of developing rats. Int J Dev Neurosci. 9(1):39-46, 1991. DeNoble, V. J. Vinpocetine enhances retrieval of a step-through passive avoidance response in rats. Pharmacol Biochem Behav. 26(1):183-186, 1987. DeNoble, V. J., et al. Vinpocetine: nootropic effects on scopolamine-induced and hypoxia-induced retrieval deficits of a step-through passive avoidance response in rats. Pharmacology, Biochemistry and Behavior. 24(4):1123-1128, 1986. Farr, S. A., et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 84(5):1173-1183, 2003. Formenti, A., et al. Effects of acetyl-L-carnitine on the survival of adult rat sensory neurons in primary cultures. Int J Dev Neurosci. 10:207-214, 1992. Hagen, T. M., et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA. 99(4):1870-1875, 2002. Liu, J., et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci USA. 99(4):2356-2361, 2002. Liu, J., et al. Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. , 2004. Manconi, E., et al. A double-blind clinical trial of vinpocetine in the treatment of cerebral insufficiency of vascular and degenerative origin. Curr Ther Res Clin Exp. 40:702-709, 1986. Mayeux R and Sano M. Treatment of Alzheimer's Disease. N Engl J Med 341:1670-9, 1999. McKay Hart, A., et al. Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment. Neurosci Lett. 334:181-185, 2002. Miyamoto, M., et al. Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. J Pharmacol Exp Ther. 250:1132-1140, 1989. Napoleone, P., et al. Age-dependent nerve cell loss in the brain of Sprague-Dawley rats: effect of long term acetyl-L-carnitine treatment. Arch Gerontol Geriatr. 10:173-185, 1990. Packer, L., et al. Alpha-lipoic acid as a biological antioxidant. Free Rad Biol Med. 19:227-250, 1995 Passeri M., et al. Acetyl-L-carnitine in the treatment of mildly demented elderly patients. . 1990. Polich J. and Gloria R. Cognitive effects of a Ginkgo biloba/vinpocetine compound in normal adults: systematic assessment of perception, attention and memory. Hum Psychopharmacol 16:409-16, 2001. Postiglione, A., et al. Effect of acute administration of L-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct. , 1991 Ramacci, M. T., et al. Effect of long-term treatment with acetyl-L-carnitine on structural changes of ageing rat brain. Drugs Exp Clin Res. 14(9):593-601, 1988. Reed, K. W., et al. Acetylcarnitine and cholinergic receptors. J Pharm Sci. 69:1065-1068, 1980. Salvioli, G. and Neri, M. L-acetylcarnitine treatment of mental decline in the elderly. , 1994. Santos, M., et al. Synaptosomal response to oxidative stress: effect of vinpocetine. Free Radic Res. 32:57-66, 2000. Stoll, S., et al. The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits. Pharm Biochem Behav. 46:799-805, 1993. Subhan, Z., et al. Psychopharmacological effects of vinpocetine in normal healthy volunteers. Eur J Clin Pharmacol. 28(5):567-571, 1985. Taglialatela, G., et al. Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide. Neurochem Res. 20:1-9, 1995. Valerio, C., et al. The effects of acetyl-L-carnitine on experimental models of learning and memory deficits in the old rat. Funct Neurol. 4:387-390, 1989. Wolz, P., et al. Effect of DL-alpha-lipoic acid on the status of lipid peroxidation and protein oxidation in various brain regions of aged rats. J Nutr Biochemistry. 13:619-624, 2002.