Thymenol™ - Single Bottle (30 Servings)

$69.95 USD

[ Details ]

Thymenol™, utilizing an innovative Cap-in-Cap Technology, offers a multi-phase release of ThymoQuin™ and Pycnogenol® via a small prefilled powder cap that is inside of a larger liquid-filled capsule. This blend of ingredients is especially unique as the technology allows the delivery of fat- and water-soluble antioxidants in a single serving.*ThymoQuin™, a clinically studied ingredient standardized to 3% thymoquinone content from black cumin seed, provides unique antioxidant activity.  Specifically, ThymoQuin™ limits fat peroxidation—the degradation of lipids where free radicals "steal" electrons from the lipids in cell membranes, —with healthy cellular aging properties. Thymenol™ is highly beneficial for the cardiovascular system, the endocrine system as well as it promotes healthy immune cell activity. ThymoQuin™ has shown to be protective of liver cells from internal free radical impact, demonstrating a healthy inflammatory response.*Pycnogenol® is a plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. Pycnogenol®, a powerful antioxidant, selectively binds to collagen and elastin and promotes the normal production of endothelial nitric oxide, which promotes the normal dilation of blood vessels and blood flow to the brain as well as other vital tissues.* Pycnogenol® is one of the most clinically researched ingredients in the natural health space.** These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Benefits

  • Cap-in-Cap Technology
  • Provides controlled-multiphase release of ingredients
  • Promotes healthy blood flow to the brain
  • Helps promote/supports cardiovascular health
  • Promotes / Supports healthy blood vessel dilation/function
  • Helps maintain normal blood pressure
  • Promotes / Supports healthy nitric oxide levels
  • Helps maintain normal levels of cholesterol
  • Helps maintain normal levels of triglycerides
  • Helps maintain normal levels of LDL and HDL particles
  • Helps support normal hormonal balance in both men and women
  • Supports normal reproductive health
  • Demonstrates a healthy inflammatory response
  • Supports cellular health and function
  • Supports healthy cellular aging
  • Promotes feelings of physical & mental comfort
  • Promotes feelings of calmness
  • Helps maintain normal healthy levels of triglycerides
  • Helps maintain normal blood glucose levels
  • Supports healthy weight
  • Multi-action antioxidant – coverage for both fat and water soluble tissues
  • Powerful antioxidant, protecting the body from the effects of free radicals
  • Supports normal respiratory health/function
  • May assist the body in optimizing/maintaining gastric tone and comfort
  • Supports memory, cognition and attention
  • Supports healthy brain function
  • Helps balance emotions in stressful situations
  • Promotes healthy immune cell activity

Product Classifications

Product Classifications

Gluten-Free – the finished product contains no detectable gluten (<10ppm gluten)

No Detectable GMOs – the finished product contains no detectable genetically-modified organism

Vegetarian – Thymenol is a vegetarian product

Why Choose Thymenol?

Thymenol, utilizing an innovative Cap-in-Cap Technology, offers a multi-phase release of ThymoQuin and Pycnogenol® via a small prefilled powder cap that is inside of a larger liquid-filled capsule. This blend of ingredients is especially unique as the technology allows the delivery of fat- and water-soluble antioxidants in a single serving.*

ThymoQuin™, a clinically studied ingredient standardized to 3% thymoquinone content from black cumin seed, provides unique antioxidant activity.  Specifically, ThymoQuin™ limits fat peroxidation—the degradation of lipids where free radicals "steal" electrons from the lipids in cell membranes, —with healthy cellular aging properties. ThymoQuin™ is highly beneficial for the cardiovascular system, the endocrine system as well as it promotes healthy immune cell activity. ThymoQuin™ has shown to be protective of liver cells from internal free radical impact, demonstrating a healthy inflammatory response.*

Pycnogenol® is a plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. Pycnogenol®, a powerful antioxidant, selectively binds to collagen and elastin and promotes the normal production of endothelial nitric oxide, which promotes the normal dilation of blood vessels and blood flow to the brain as well as other vital tissues.* Pycnogenol® is one of the most clinically researched ingredients in the natural health space.*

Ingredients

ThymoQuin™ Black Cumin Seed (Nigella sativa) (3% thymoquinone)—500 mg per serving:
ThymoQuin is a standardized extract derived from black cumin seed, containing a volatile oil called thymoquinone. Thymoquinone, because of its terpenoid content (para-cymene), may support the cellular activity of other ingredients it is paired with while also supporting improved bioavailability. Nigella sativa (black cumin seed) is a plant that has been used throughout the world for centuries. Due to its various effects, this plant has a multitude of potential applications. This standardization of thymoquinone sets this product apart from the competition. ThymoQuin is evidenced to boost the benefits of both fat soluble and water-soluble antioxidants and fatty acids for cellular health, while having its own glycemic, cardiovascular and mental well-being benefits.*

Pycnogenol® – 25mg per serving:
Published findings have demonstrated Pycnogenol’s wide array of beneficial effects on the body. Pine bark extract is a combination of procyanidins, bioflavonoids and organic acids.*

Pycnogenol is a powerful scavenger of free radicals. Its antioxidant capabilities help promote cardiovascular health, help maintain normal blood pressure, help maintain normal levels of triglycerides, support normal reproductive health, demonstrate healthy inflammatory response, supports healthy cellular aging and helps support normal hormonal balance in both men and women.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

*Pycnogenol is a registered trademark of Horphag Research (UK) Ltd.

*ThymoQuin is a trademark of TriNutra Ltd.

FAQs

Who should use Thymenol™?
Those that want to boost the benefits of their daily supplement regimen with the powerful ingredients found in Black Cumin Seed and French Martime Pine Bark Extract while also getting the calming benefits of ThymoQuin™. *

What makes the cap-in-cap delivery system better than taking two separate products?
The Cap-in-Cap technology featured in Thymenol™ allows for a unique combination of normally incompatible ingredients (oil and powder). The technology features a small prefilled powder cap inside of a larger liquid-filled capsule, which allows for a multi-phase release of ThymoQuin™ and Pycnogenol®. This technology offers you one of the most superior products on the market.

Should I still take Isotonix OPC-3® if I take Thymenol™?
Yes. The benefits of the five different antioxidants in OPC-3 make it the perfect complimentary supplement to Thymenol™.

Can I take Thymenol™ and CannabiQuin™ at the same time?
Yes. It is safe to take Thymenol™ and CannabiQuin™ together. Thymenol™ is formulated for cardio, cognitive and immune support. CannabiQuin™ demonstrates a healthy inflammatory response, promotes feelings of physical and mental comfort.*

What is the best time of day to use Thymenol™?
Take two capsules daily with or without food, anytime of day.

Why is ThymoQuin™ superior over other black cumin seed oils?
ThymoQuin™, cold-pressed for better preservation of the whole composition of the seed without the use of solvent, is the first and only standardized black cumin seed oil on the market. When you use a standardized ingredient, you get consistent health benefits and a consistent finished product.*

Why was ThymoQuin™ paired with Pycnogenol®?
ThymoQuin™ by itself has many health benefits, but the real power of ThymoQuin™ is in combination with other ingredients. Studies show that ThymoQuin™ boosts anti-inflammatory potential of the other ingredients in the formulation; therefore, the healthy impact of the combination product is more than the ingredients taken separately.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Science

Ahmad A, Husain A, Mujeeb M, et al. A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed. 2013;3(5):337–352.

Am J Otolaryngol. 2011 Sep-Oct; 32(5):402-7.Ansari MA, Ansari NA, Junejo SA. Montelukast versus Nigella sativa for management of seasonal allergic rhinitis: a single blind comparative clinical trial. Pak J Med Sci. 2010;26(2):249–54.

Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Dehkordi FR, Kamkhah AF Fundam Clin Pharmacol. 2008 Aug; 22(4):447-52.

Avicenna J Phytomed. 2016 Jan-Feb;6(1):34-43.

Avicenna J Phytomed. 2016 Jan-Feb;6(1):34-43.Bag, A., & Chattopadhyay, R. R. (2015). Evaluation of synergistic antibacterial and antioxidant efficacy of essential oils of spices and herbs in combination. PloS one, 10(7), e0131321.

Bayeta, E., et al. Pycnogenol® inhibits generation of inflammatory mediators in macrophages. Nutrition Research 20: 249-259, 2000.

Blazsó, G., et al. Anti-inflammatory and superoxide radical scavenging activities of a procyanidins containing extract from the bark of Pinus pinaster Sol. and its fractions. Pharm Pharmacol Lett 3: 217-20, 1994.

Blood pressure lowering effect of Nigella sativa L. seed oil in healthy volunteers: a randomized, double-blind, placebo-controlled clinical trial. Fallah Huseini H, Amini M, Mohtashami R, Ghamarchehre ME, Sadeqhi Z, Kianbakht S, Fallah Huseini A Phytother Res. 2013 Dec; 27(12):1849-53.

Bordoni L, Fedeli D, Nasuti C, et al. Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes. Antioxidants (Basel). 2019;8(2):51. Published 2019 Feb 25. doi:10.3390/antiox8020051

Boskabady, Mohammad Hossein & Vahedi, Nassim & Amery, Sediqa & Khakzad, Mohamad. (2011). The effect of Nigella sativa alone, and in combination with dexamethasone, on tracheal muscle responsiveness and lung inflammation in sulfur mustard exposed guinea pigs. Journal of ethnopharmacology. 137. 1028-34. 10.1016/j.jep.2011.07.030.

Chehl N, Chipitsyna G, Gong Q, Yeo CJ, Arafat HA. Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. HPB (Oxford). 2009;11(5):373–381. doi:10.1111/j.1477-2574.2009.00059.x

Cho, K., et al. Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interlukin-1 production in lipopolysaccharide-stimulated RAW 264. 7. Toxicology and Applied Pharmacology 168: 64-71, 2000.

Cho, K., et al. Inhibition mechanisms of bioflavonoids extracted from the bark of Pinus maritima on the expression of proinflammatory cytokines. Annals of the NY Academy of Sciences 928: 141-156, 2001.

Choi YH, Yan GH. Pycnogenol®®® inhibits immunoglobulin E-mediated allergic response in mast cells. Phytother Res 23: 1691-1695, 2009.

Datau EA, Wardhana, Surachmanto EE, Pandelaki K, Langi JA, Fias.  Efficacy of Nigella sativa on serum free testosterone and metabolic disturbances in central obese male. Acta Med Indones.  Jul;42(3):130-4, 2010.

Effect of Nigella sativa oil on various clinical and biochemical parameters of insulin resistance syndrome. Najmi A, Nasiruddin M, Khan RA, Haque SF Int J Diabetes Dev Ctries. 2008 Jan; 28(1):11-4.

Effectiveness of Nigella sativa oil in the management of rheumatoid arthritis patients: a placebo controlled study. Gheita TA, Kenawy SA Phytother Res. 2012 Aug; 26(8):1246-8.

Efficacy and safety of honey based formulation of Nigella sativa seed oil in functional dyspepsia: A double blind randomized controlled clinical trial. Mohtashami R, Huseini HF, Heydari M, Amini M, Sadeqhi Z, Ghaznavi H, Mehrzadi S J Ethnopharmacol. 2015 Dec 4; 175():147-52.

Entok E1, Ustuner MC, Ozbayer C, Tekin N, Akyuz F, Yangi B, Kurt H, Degirmenci I, Gunes HV.; “Anti-inflammatuar and anti-oxidative effects of Nigella sativa L.: 18FDG-PET imaging of inflammation,” Mol Biol Rep. 2014 May, PMID: 2447466

Farhangi MA, Dehghan P, Tajmiri S, Abbasi MM. The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial. BMC Complement Altern Med. 2016 Nov 16;16(1):471.

Farzaneh E1, Nia FR2, Mehrtash M2, Mirmoeini FS3, Jalilvand M1.; “The Effects of 8-week Nigella sativa Supplementation and Aerobic Training on Lipid Profile and VO2 max in Sedentary Overweight Females,” Int J Prev Med., 2014 February, PMID: 24627749

Fine, AM. Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Altern Med Rev 5:144-51, 2000. Review.

Fitzpatrick, D., et al. Endothelium-dependent vascular effects of Pycnogenol®. Journal of Cardiovascular Pharmacology 32: 509-515, 1998.

Golshan Iranpour F, Fazelian K, Dashti GR. Thymoquinone as a natural spermostatic substance in reproductive medicine: An experimental study. Int J Reprod Biomed (Yazd). 2017 Oct;15(10):641-648.

Gulati, O. Pycnogenol® in venous disorders: a review. European Bulletin of Drug Research 7: 1-13, 1999.

Herbal treatment of allergic rhinitis: the use of Nigella sativa. Nikakhlagh S, Rahim F, Aryani FH, Syahpoush A, Brougerdnya MG, Saki N

Hosseini, S., et al. Pycnogenol® in the management of asthma. Journal of Medicinal Food 4: 201-209, 2001.

Kolahdooz M, Nasri S, Modarres SZ, Kianbakht S, Huseini HF.Effects of Nigella sativa L. seed oil on abnormal semen quality in infertile men: a randomized, double-blind, placebo-controlled clinical trial. Phytomedicine. 2014 May 15;21(6):901-5. doi: 10.1016/j.phymed.2014.02.006.

Lau B et al. Pycnogenol® as an adjunct in the management of childhood asthma. J Asthma. 41(8):825-32, 2004.

Lei, X., Liu, M., Yang, Z. et al. Dig Dis Sci (2012) 57: 2296. https://doi.org/10.1007/s10620-012-2156-x

Maffei A, Charrier C, Caiati MD, et al. Emerging Mechanisms Underlying Dynamics of GABAergic Synapses. J Neurosci. 2017;37(45):10792–10799. doi:10.1523/JNEUROSCI.1824-17.2017

Majdalawieh, Amin & Fayyad, Muneera. (2015). Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review. International immunopharmacology. 28. 295-304. 10.1016/j.intimp.2015.06.023.

Masood Sadiq Butt & Muhammad Tauseef Sultan (2010) Nigella sativa: Reduces the Risk of Various Maladies, Critical Reviews in Food Science and Nutrition, 50:7,654-665, DOI: 10.1080/10408390902768797 Planta Med. 2016 Jan;82(1-2):8-16.

Mohebbati R, Hosseini M, Haghshenas M, Nazariborun A, Beheshti F. The effects of Nigella Sativa extract on renal tissue oxidative damage during neonatal and juvenile growth in propylthiouracil-induced hypothyroid rats. Endocr Regul. 2017 Apr 25;51(2):105-113. doi: 10.1515/enr-2017-0010.

Nigella Sativa oil (5 mL/day) used in combination with atorvastatin and metformin could decrease metabolic syndrome fasting blood sugar (FBS), LDL, and TC significantly after six weeks of use

Packer, L., et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, Pycnogenol®®. Free Radic Biol Med 27:704-24, 1999. Review.

Padhye S, Banerjee S, Ahmad A, Mohammad R, Sarkar FH. From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. Cancer Ther. 2008;6(b):495–510.

Pharmacol Rep. 2016 Aug;68(4):671-9. doi: 10.1016/j.pharep.2016.03.014. Epub 2016 Apr 8.

Pulm Pharmacol Ther. 2009 Feb;22(1):37-43.

Rabab El Mezayen, Mohamed El Gazzar, Mark R. Nicolls, John C. Marecki, Stephen C. Dreskin, Hisayuki Nomiyama. Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. Immunology Letters 2006 Jul 15;106(1):72-81. doi.org/10.1016/j.imlet.2006.04.012.

Randhawa, Mohammad & Al-Ghamdi, Mastour. (2011). Anticancer Activity of Nigella sativa (Black Seed) - A Review. The American journal of Chinese medicine. 39. 1075-91. 10.1142/S0192415X1100941X.

Rohdewald, P. A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther 40:158-68, 2002. Review.

Salem ML.; “Immunomodulatory and therapeutic properties of the Nigella sativa L. seed,” Int Immunopharmacol. 2005 Dec, PMID: 16275613.

Sayeed MSB, Asaduzzaman M, Morshed H, et al. The effect of Nigella sativa Linn seed on memory, attention and cognition in healthy human volunteers. J Ethnopharmacol. 2013;148(3):780–786

 

Sharma SC, Sharma S, Gulati OP. Pycnogenol® inhibits the release of histamine from mast cells. Phytother Res, 17: 66-69, 2003.

Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone. J Pharmacopuncture. 2017;20(3):179–193. doi:10.3831/KPI.2017.20.021

Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone. J Pharmacopuncture. 2017;20(3):179–193.

Vanamala J1, Kester AC, Heuberger AL, Reddivari L.; “Mitigation of obesity-promoted diseases by Nigella sativa and thymoquinone,” Plant Foods Hum Nutr. 2012 Jun, PMID: 22477645

Wang ZJ, Heinbockel T. Essential Oils and Their Constituents Targeting the GABAergic System and Sodium Channels as Treatment of Neurological Diseases. Molecules. 2018;23(5):1061. Published 2018 May 2. doi:10.3390/molecules23051061

Watson, R. Pycnogenol® and cardiovascular health. Evidence-Based Integrative Medicine 1: 27-32, 2003.

Wilson D et al. A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of Pycnogenol® for improving allergic rhinitis symptoms. Phytother Res. 24(8):1115-9, 2010.

 

*These statements have not been evaluated by the Food and Drug Administration.
This product(s) is not intended to diagnose, treat, cure or prevent any disease.

Reviews

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My skin looks better

My skin is more radiant after 1month. Just love it

Response from Customer Service:
December 8, 2019

Dear Valued Customer,

Thank you for taking the time to leave your thoughts on the Thymenol™. We are happy to hear you are pleased with the product.

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Very Effective

I can sleep through the night; haven't done that in over 25 years!
My memory recall is faster and more consistent.
I won't go a day without it.

Response from Customer Service:
December 3, 2019

Dear Valued Customer,

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A double punch

Wow, putting these two amazing products together in this cap in cap technology. Such a strong anti-inflammatory.

Response from Customer Service:
December 2, 2019

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INCREDIBLE!!!

I CAN BELIEVE IT SO EFFICIENTLY WORK ON MY BUSY DAY TO EASY RELEASE MY BODY FATIGUE.

Response from Customer Service:
December 2, 2019

Dear Valued Customer,

Thank you for taking the time to leave your thoughts on the Thymenol. We are happy to hear you are pleased with the product.

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#pycnogenol and Black Seed Oil?? YES PLEASE!!!

I couldn't wait to try this product and it did not disappoint! Since going thru menopause I've been looking for a product to support relief from the "brain fog" I was experiencing. THIS IS IT. I feel more alert and like "my old self " again!! Cannot recommend it highly enough.

Response from Customer Service:
October 30, 2019

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